Prognostic and clinicopathological significance of long noncoding RNA CTD-2510F5.4 in gastric cancer.

ABSTRACT:

Background

Compelling studies have demonstrated the correlation between aberrant expressed lncRNAs and human cancers, and revealed promise of these lncRNAs as biomarkers in predicting patients' survival and outcome.

Methods

We downloaded the RNA-seq data from the Cancer Genome Atlas, and screened out DEGs and DELs between gastric cancer tissues and normal gastric tissues. By bioinformatics analysis, we identified CTD-2510F5.4 was a malignant phenotype associated lncRNA. The expression levels of CTD-2510F5.4 in tissues were detected by ISH, and the relationships between CTD-2510F5.4 expression and clinicopathological characteristics were analyzed by statistical analysis.

Results

By bioinformatics analysis and functional analysis, we identified CTD-2510F5.4 was a malign

SUBMITTER: Wang Z 

PROVIDER: S-EPMC6570689 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature