Prevalence and risk factors for impaired kidney function in the district of Anuradhapura, Sri Lanka: a cross-sectional population-representative survey in those at risk of chronic kidney disease of unknown aetiology.

ABSTRACT:

Background

Over the last 20 years there have been reports of a form of chronic kidney disease of unknown cause (CKDu) affecting rural communities in the North Central Province of Sri Lanka. Valid prevalence estimates, using a standardised methodology, are needed to assess the burden of disease, assess secular trends, and perform international comparisons.

Methods

We conducted a cross-sectional representative population survey in five study areas with different expected prevalences of CKDu. We used a proxy definition of CKDu involving a single measure of impaired kidney function (eGFR< 60 mL/min/1.7m², using the CKD-Epi formula) in the absence of hypertension, diabetes or heavy proteinuria.

Results

A total of 4803 participants (88.7%) took part in the study

SUBMITTER: Ruwanpathirana T 

PROVIDER: S-EPMC6570843 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature