Experimental infection of Korean native goats (Capra aegagrus hircus) with bovine viral diarrhea virus 1b.

ABSTRACT:

Background

Bovine viral diarrhea virus (BVDV) infects various ungulates and causes reproductive failure in infected goats. BVDV has been detected among goats in the Republic of Korea, but the route of transmission remains unclear. Here, we aimed to investigate whether BVDV-1b circulating among Korean cattle can be transmitted to Korean native goats (Capra aegagrus hircus) and characterize the outcomes of BVDV infection in these goats.

Results

Four goats were inoculated intranasally with the Korean noncytopathic (ncp) BVDV-1b strain. Two goats exhibited clinical signs of illness, including coughing and nasal discharge. Nasal swabs and blood were collected to screen for viral RNA and BVDV antibodies. Using the 5'-untranslated region (UTR), viral RNA was detected in the nasal s

SUBMITTER: Oem JK 

PROVIDER: S-EPMC6570889 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature