Poor awareness of IADL deficits is associated with reduced regional brain volume in older adults with cognitive impairment.

ABSTRACT: Performance of instrumental activities of daily living (IADLs) can become compromised in older adults with mild cognitive impairment (MCI). Patients' level of insight into their everyday functioning varies both amongst individuals and across domains assessed, with some individuals exhibiting complete unawareness of deficits. The current cross-sectional study examined the neuroanatomical substrates of self-awareness in order to help explain the variability in this phenomenon in older adults across a continuum of cognitive impairment. Eighty-five participants (ages 54-88, mean age = 73 years, 57% female, 89% Caucasian) diagnosed with MCI or mild probable dementia underwent structural magnetic resonance imaging. Level of self-awareness was assessed by calculating the discrepancy between objec

SUBMITTER: Steward KA 

PROVIDER: S-EPMC6571164 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature