Rare genetic variation and balanced polymorphisms are important for survival in global change conditions.

ABSTRACT: Standing genetic variation is important for population persistence in extreme environmental conditions. While some species may have the capacity to adapt to predicted average future global change conditions, the ability to survive extreme events is largely unknown. We used single-generation selection experiments on hundreds of thousands of Strongylocentrotus purpuratus sea urchin larvae generated from wild-caught adults to identify adaptive genetic variation responsive to moderate (pH 8.0) and extreme (pH 7.5) low-pH conditions. Sequencing genomic DNA from pools of larvae, we identified consistent changes in allele frequencies across replicate cultures for each pH condition and observed increased linkage disequilibrium around selected loci, revealing selection on recombined standing geneti

SUBMITTER: Brennan RS 

PROVIDER: S-EPMC6571474 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature