Association between Serum Urate and Risk of Hypertension in Menopausal Women with XDH Gene.

ABSTRACT: Elevated serum urate (sUA) concentrations have been associated with an increased risk of hypertension. We aimed to examine the association of sUA concentration on the risk of hypertension in pre- and post-menopausal women and investigated the association between the polymorphism of the xanthine dehydrogenase gene and the risk of hypertension. Among 7294 women, 1415 premenopausal and 5879 postmenopausal women were recruited. Anthropometric parameters as risk factors of hypertension were identify by logistic regression models. In addition, we investigated an association between xanthine dehydrogenase gene and sUA and their combined associations on the risk of hypertension. Body mass index (BMI) and waist circumference (WC) were significantly increased in accordance to the increase of sUA lev

SUBMITTER: Lee JH 

PROVIDER: S-EPMC6571698 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature