Insecticidal Activity of Four Lignans Isolated from Phryma leptostachya.

ABSTRACT: A new lignan (T4) and three known lignans (T1, T2, and T3) were isolated from the methanol extract of the roots of Phryma leptostachya using bioassay-guided method, and their structures were identified as phrymarolin I (T1), II (T2), haedoxan A (T3), and methyl 4-((6a-acetoxy-4-(6-methoxybenzo[d][1,3]dioxol-5-yl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl)oxy)-1-hydroxy-2,2-dimethoxy-5-oxocyclopent-3-ene-1-carboxylate (T4) byNMR and ESI-MS spectral data. Bioassay results revealed that haedoxan A exhibited remarkably high insecticidal activity against Mythimna separata with a stomach toxicity LC₅₀ value of 17.06 mg/L and a topical toxicity LC₅₀ value of 1123.14 mg/L at 24 h, respectively. Phrymarolin I an

SUBMITTER: Li Y 

PROVIDER: S-EPMC6572576 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature