Outcomes of Radiation-Associated Esophageal Squamous Cell Carcinoma: The MSKCC Experience.

ABSTRACT:

Objective

Esophageal squamous cell carcinoma (ESCC-R) is a rarely encountered sequela of chest radiation. Treatment is limited by toxicity with reirradiation and complex surgical dissection in a previously radiated field. The clinical presentation, prognosis, and treatment selection of ESCC-R remain undefined.

Methods

A retrospective review of patients with esophageal squamous cell carcinoma at a single institution between 2000 and 2017 was performed to identify patients with previous radiation therapy (≥ 5 years delay). Clinicopathologic characteristics, treatment, and outcomes of ESCC-R (n = 69) patients were compared to patients with primary esophageal squamous cell carcinoma (ESCC) (n = 827). Overall survival (OS) and cumulative incidence of recurrence (CIR) were compare

SUBMITTER: Nobel TB 

PROVIDER: S-EPMC6572721 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature