Arginine Metabolism in Supragingival Oral Biofilms as a Potential Predictor of Caries Risk.

ABSTRACT:

Introduction

Ammonia production via the arginine deiminase system (ADS) of oral bacteria can function to reduce the cariogenicity of oral biofilms by neutralizing glycolytic acids that cause tooth demineralization.

Objectives

This cohort study investigated the relationship between ADS activity and bacterial profile changes of supragingival biofilms with caries experience among children over time.

Methods

A total of 79 children aged 2 to 7 y at baseline were assessed every 6 mo for a period of 18 mo. Children were grouped as caries free (CF), caries active with enamel lesions (CAE), or caries active with dentin lesions (CA). Supragingival plaque samples were collected from caries-free surfaces (PF) and from enamel (PE) and dentin (PD) lesions. Plaque ADS activity was m

SUBMITTER: Nascimento MM 

PROVIDER: S-EPMC6572888 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature