Smoking and atherosclerotic cardiovascular disease risk in young men: the Korean Life Course Health Study.

ABSTRACT:

Objective

To examine the effect of smoking on risk of atherosclerotic cardiovascular disease (ASCVD) in Korean young men and to examine whether serum total cholesterol levels could modify the effect of smoking on ASCVD.

Design

A prospective cohort study within a national insurance system.

Setting

Health screenings provided by national insurance in 1992 and 1994.

Participants

A total of 118 531 young men between 20 and 29 years of age and were followed up for an average of 23 years.

Outcome measure

To assess the independent effects of smoking on the risk of ischaemic heart disease (IHD), stroke and ASCVD, Cox proportional hazards regression models were used, controlling for age, hypertension, diabetes, hypercholesterolaemia and alcohol drinking.

Result

SUBMITTER: Jee Y 

PROVIDER: S-EPMC6575821 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature