Comparative transcriptomics of 3 high-altitude passerine birds and their low-altitude relatives.

ABSTRACT: High-altitude environments present strong stresses for living organisms, which have driven striking phenotypic and genetic adaptations. While previous studies have revealed multiple genetic adaptations in high-altitude species, how evolutionary history (i.e., phylogenetic background) contributes to similarity in genetic adaptations to high-altitude environments is largely unknown, in particular in a group of birds. We explored this in 3 high-altitude passerine birds from the Qinghai-Tibet Plateau and their low-altitude relatives in lowland eastern China. We generated transcriptomic data for 5 tissues across these species and compared sequence changes and expression shifts between high- and low-altitude pairs. Sequence comparison revealed that similarity in all 3 high-altitude species was h

SUBMITTER: Hao Y 

PROVIDER: S-EPMC6576129 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature