Association of Habitual Coffee Consumption and HECTD4 Polymorphism with Risk of Prediabetes and Type 2 Diabetes (P18-071-19)

ABSTRACT: Abstract

Objectives

Epidemiological studies suggested the evidence that coffee consumption decreased risk of type 2 diabetes. Recently, Japanese genome-wide association studies (GWAS) of coffee consumption has identified rs2074356 (G > A) at 12q24.12–13 in HECTD4. This study aims to examine the associations of habitual coffee consumption with prediabetes and type 2 diabetes, and whether this association is modified by rs2074356 variant in Korean adults.

Methods

A total of 4010 participants (1890 men and 2120 women) who had genetic information from Korea Association REsource (KARE) study were included. Habitual coffee consumption was assessed through a food frequency questionnaire and categorized into five categories (non-consumers, <1 cup/day and ≥1 cups/day of black coff

SUBMITTER: Jin T 

PROVIDER: S-EPMC6577398 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature