The Restrictive IV Fluid Trial in Severe Sepsis and Septic Shock (RIFTS): A Randomized Pilot Study.

ABSTRACT:

Objectives

It is unclear if a low- or high-volume IV fluid resuscitation strategy is better for patients with severe sepsis and septic shock.

Design

Prospective randomized controlled trial.

Setting

Two adult acute care hospitals within a single academic system.

Patients

Patients with severe sepsis and septic shock admitted from the emergency department to the ICU from November 2016 to February 2018.

Interventions

Patients were randomly assigned to a restrictive IV fluid resuscitation strategy (≤ 60 mL/kg of IV fluid) or usual care for the first 72 hours of care.

Measurements and main results

We enrolled 109 patients, of whom 55 were assigned to the restrictive resuscitation group and 54 to the usual care group. The restrictive group received signi

SUBMITTER: Corl KA 

PROVIDER: S-EPMC6579683 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature