Impact of Percutaneous Revascularization on Exercise Hemodynamics in Patients With Stable Coronary Disease.

ABSTRACT:

Background

Recently, the therapeutic benefits of percutaneous coronary intervention (PCI) have been challenged in patients with stable coronary artery disease (SCD).

Objectives

The authors examined the impact of PCI on exercise responses in the coronary circulation, the microcirculation, and systemic hemodynamics in patients with SCD.

Methods

A total of 21 patients (mean age 60.3 ± 8.4 years) with SCD and single-vessel coronary stenosis underwent cardiac catheterization. Pre-PCI, patients exercised on a supine ergometer until rate-limiting angina or exhaustion. Simultaneous trans-stenotic coronary pressure-flow measurements were made throughout exercise. Post-PCI, this process was repeated. Physiological parameters, rate-limiting symptoms, and exercise performance wer

SUBMITTER: Cook CM 

PROVIDER: S-EPMC6580361 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature