Long-term Cognitive Outcomes in Patients With Pediatric-Onset vs Adult-Onset Multiple Sclerosis.

ABSTRACT:

Importance

Cognitive impairment in multiple sclerosis (MS) can lead to reduced quality of life, social functioning, and employment. Few studies have investigated cognitive outcomes among patients with pediatric-onset MS (POMS) over the long term.

Objective

To compare long-term information-processing efficiency between patients with POMS and adult-onset MS (AOMS).

Design, setting, and participants

This population-based longitudinal cohort study accessed the Swedish MS Registry (SMSreg), which collates information from all 64 neurology clinics in Sweden. Registered cases with definite MS in the SMSreg with an onset before April 15, 2018, and at least 2 Symbol Digit Modalities Test (SDMT) scores recorded were included. Only persons aged 18 to 55 years and with duration o

SUBMITTER: McKay KA 

PROVIDER: S-EPMC6580443 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature