CO₂ and O₂ removal during continuous veno-venous hemofiltration: a pilot study.

ABSTRACT:

Background

Carbon dioxide (CO₂) accumulation is a challenging issue in critically ill patients. CO₂ can be eliminated by renal replacement therapy but studies are scarce and clinical relevance is unknown. We prospectively studied CO₂ and O₂ behavior at different sample points of continuous veno-venous hemofiltration (CVVH) and build a model to calculate CO₂ removal bedside.

Methods

In 10 patients receiving standard CVVH under citrate anticoagulation, blood gas analysis was performed at different sample points within the CVVH circuit. Citrate was then replaced by NaCl 0.9% and sampling was repeated. Total CO₂ (tCO₂), CO₂ flow (V̇CO₂) and O₂ flow (V̇O₂) were

SUBMITTER: Jonckheer J 

PROVIDER: S-EPMC6580471 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature