Hypercortisolism and primary aldosteronism caused by bilateral adrenocortical adenomas: a case report.

ABSTRACT:

Background

Co-existing Cushing's syndrome and primary aldosteronism caused by bilateral adrenocortical adenomas, secreting cortisol and aldosterone, respectively, have rarely been reported. Precise diagnosis and management of this disorder constitute a challenge to clinicians due to its atypical clinical manifestations and laboratory findings.

Case presentation

We here report a Chinese male patient with co-existing Cushing's syndrome and primary aldosteronism caused by bilateral adrenocortical adenomas, who complained of intermittent muscle weakness for over 3 years. Computed tomography scans revealed bilateral adrenal masses. Undetectable ACTH and unsuppressed cortisol levels by dexamethasone suggested ACTH-independent Cushing's syndrome. Elevated aldosterone to renin ratio

SUBMITTER: Ren K 

PROVIDER: S-EPMC6580498 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature