FastProNGS: fast preprocessing of next-generation sequencing reads.

ABSTRACT:

Background

Next-generation sequencing technology is developing rapidly and the vast amount of data that is generated needs to be preprocessed for downstream analyses. However, until now, software that can efficiently make all the quality assessments and filtration of raw data is still lacking.

Results

We developed FastProNGS to integrate the quality control process with automatic adapter removal. Parallel processing was implemented to speed up the process by allocating multiple threads. Compared with similar up-to-date preprocessing tools, FastProNGS is by far the fastest. Read information before and after filtration can be output in plain-text, JSON, or HTML formats with user-friendly visualization.

Conclusions

FastProNGS is a rapid, standardized, and user-friendly t

SUBMITTER: Liu X 

PROVIDER: S-EPMC6580563 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature