Is atopy a risk indicator of chronic obstructive pulmonary disease in dairy farmers?

ABSTRACT: Allergic mechanisms related to environmental and occupational exposure have been suggested to contribute to the development of chronic obstructive pulmonary disease (COPD).

Objectives

To investigate the relationships between atopy markers, persistent airflow limitation (PAL) and occupational exposure in dairy farmers.

Methods

Clinical and biological (total IgE and 21 allergen specific IgE) markers of atopy were assessed in 101 dairy farmers with PAL (DF-PAL), 85 non-farmers with PAL (NF-PAL) (both groups were prospectively included from a screening program performed between 2011 and 2015), and matched controls, i.e. 98 farmers without PAL (DF-controls) and 89 non-farming subjects without PAL (NF-controls). Occupational exposure in farmers was estimated using a validated quest

SUBMITTER: Veil-Picard M 

PROVIDER: S-EPMC6580567 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature