Long-Term Outcome after Prolonged Mechanical Ventilation. A Long-Term Acute-Care Hospital Study.

ABSTRACT: Rationale: Patients managed at a long-term acute-care hospital (LTACH) for weaning from prolonged mechanical ventilation are at risk for profound muscle weakness and disability. Objectives: To investigate effects of prolonged ventilation on survival, muscle function, and its impact on quality of life at 6 and 12 months after LTACH discharge. Methods: This was a prospective, longitudinal study conducted in 315 patients being weaned from prolonged ventilation at an LTACH. Measurements and Main Results: At discharge, 53.7% of patients were detached from the ventilator and 1-year survival was 66.9%. On enrollment, maximum inspiratory pressure (Pi_max) was 41.3 (95% confidence interval, 39.4-43.2) cm H₂O (53.1% predicted), whereas handgrip streng

SUBMITTER: Jubran A 

PROVIDER: S-EPMC6580672 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature