Working Memory Impairment Across Psychotic disorders.

ABSTRACT:

Background

Working memory (WM) has been a central focus of cognitive neuroscience research because WM is a resource that is involved in many different cognitive operations. The goal of this study was to evaluate the clinical utility of WM paradigms developed in the basic cognitive neuroscience literature, including methods designed to estimate storage capacity without contamination by lapses of attention.

Methods

A total of 61 people with schizophrenia, 49 with schizoaffective disorder, 47 with bipolar disorder with psychosis, and 59 healthy volunteers were recruited. Participants received multiple WM tasks, including two versions each of a multiple Change Detection paradigm, a visual Change Localization paradigm, and a Running Span task.

Results

Healthy volunteers pe

SUBMITTER: Gold JM 

PROVIDER: S-EPMC6581132 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature