Association of Blood Component Ratios With 24-Hour Mortality in Injured Children Receiving Massive Transfusion.

ABSTRACT:

Objectives

To determine if higher fresh frozen plasma and platelet to packed RBC ratios are associated with lower 24-hour mortality in bleeding pediatric trauma patients.

Design

Retrospective cohort study using the Pediatric Trauma Quality Improvement Program Database from 2014 to 2016.

Setting

Level I and II pediatric trauma centers participating in the Trauma Quality Improvement Program PATIENTS:: Injured children (≤ 14 yr old) who received massive transfusion (≥ 40 mL/kg total blood products in 24 hr). Of 123,836 patients, 590 underwent massive transfusion, of which 583 met inclusion criteria.

Interventions

None.

Measurements and main results

Ratios of fresh frozen plasma:packed RBC and platelet:packed RBC. Of the 583 patients, 60% were male and the m

SUBMITTER: Butler EK 

PROVIDER: S-EPMC6581209 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature