Ambient Air Pollution Exposure and Fecundability in Women Undergoing In Vitro Fertilization.

ABSTRACT:

Background

Limited research suggests ambient air pollution impairs fecundity but groups most susceptible have not been identified. We studied whether long-term ambient air pollution exposure prior to an in vitro fertilization (IVF) cycle was associated with successful livebirth, and whether associations were modified by underlying infertility diagnosis.

Methods

Data on women initiating their 1^st autologous IVF cycle in 2012-13 were obtained from four U.S. clinics. Outcomes included pregnancy, pregnancy loss, and livebirth. Annual average exposure to fine particulate matter (PM_2.5), PM₁₀, and nitrogen dioxide (NO₂) prior to IVF start were estimated at residential address using a validated national spatial model incorporating land-us

SUBMITTER: Quraishi SM 

PROVIDER: S-EPMC6581510 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature