Basic symptoms in offspring of parents with mood and psychotic disorders.

ABSTRACT:

Background

Basic symptoms, defined as subjectively perceived disturbances in thought, perception and other essential mental processes, have been established as a predictor of psychotic disorders. However, the relationship between basic symptoms and family history of a transdiagnostic range of severe mental illness, including major depressive disorder, bipolar disorder and schizophrenia, has not been examined.

Aims

We sought to test whether non-severe mood disorders and severe mood and psychotic disorders in parents is associated with increased basic symptoms in their biological offspring.

Method

We measured basic symptoms using the Schizophrenia Proneness Instrument - Child and Youth Version in 332 youth aged 8-26 years, including 93 offspring of control parents, 92 o

SUBMITTER: Zwicker A 

PROVIDER: S-EPMC6582212 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature