Lipoprotein particle concentration measured by nuclear magnetic resonance spectroscopy is associated with gestational age at delivery: a prospective cohort study.

ABSTRACT:

Objective

To estimate the association between lipoprotein particle concentrations in pregnancy and gestational age at delivery.

Design

Prospective cohort study.

Setting

The study was conducted in the USA at the University of North Carolina.

Population

We assessed 715 women enrolled in the Pregnancy, Infection, and Nutrition study from 2001 to 2005.

Methods

Fasting blood was collected at two time points (<20 and 24-29 weeks of gestation). Nuclear magnetic resonance (NMR) quantified lipoprotein particle concentrations [low-density lipoprotein (LDL), high-density lipoprotein (HDL), very-low density lipoprotein (VLDL)] and 10 subclasses of lipoproteins. Concentrations were assessed as continuous measures, with the exception of medium HDL which was classified

SUBMITTER: Grace MR 

PROVIDER: S-EPMC6582364 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature