Differential motility parameters and identification of proteomic profiles of human sperm cryopreserved with cryostraw and cryovial.

ABSTRACT:

Background

Although sperm cryopreservation has been widely used in human reproductive medicine as an integral infertility management in infertility clinics and for banking sperm in sperm banks, the freezing/thawing protocols are not optimal. The freezing and thawing processes result in changes at both structural and molecular levels, some even detrimental, in human sperm when compared with fresh sperm. The change of sperm proteins after cryopreservation may play negative roles for fertilization and early embryo development. Conventionally, cryostraws (CS) and cryovials (CV) are the most widely used cryopreservation carriers (CPCs) for human sperm cryopreservation accompanied with the use of egg yolk free commercial media. However, the influence of cryopreservation on the proteomic

SUBMITTER: Li S 

PROVIDER: S-EPMC6582484 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature