Primary hyperoxaluria diagnosed after kidney transplantation failure: lesson from 3 case reports and literature review.

ABSTRACT:

Background

Primary hyperoxaluria (PH) is a rare inborn disorder of the metabolism of glyoxylate, which causes the hallmark production oxalate and forms insoluble calcium oxalate crystals that accumulate in the kidney and other organs. Since the manifestation of PH varies from recurrent nephrolithiasis, nephrocalcinosis, and end-stage renal disease with age at onset of symptoms ranging from infancy to the sixth decade, the disease remains undiagnosed until after kidney transplantation in some cases.

Case presentation

Herein, we report 3 cases of PH diagnosed after kidney transplantation failure, providing the comprehensive clinical course, the ultrasonic image of renal graft and pathologic image of the biopsy, highlighting the relevance of biopsy findings and the results of m

SUBMITTER: Cai R 

PROVIDER: S-EPMC6582561 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature