Optimizing Genomic Prediction of Host Resistance to Koi Herpesvirus Disease in Carp.

ABSTRACT: Genomic selection (GS) is increasingly applied in breeding programs of major aquaculture species, enabling improved prediction accuracy and genetic gain compared to pedigree-based approaches. Koi Herpesvirus disease (KHVD) is notifiable by the World Organization for Animal Health and the European Union, causing major economic losses to carp production. GS has potential to breed carp with improved resistance to KHVD, thereby contributing to disease control. In the current study, Restriction-site Associated DNA sequencing (RAD-seq) was applied on a population of 1,425 common carp juveniles which had been challenged with Koi herpes virus, followed by sampling of survivors and mortalities. GS was tested on a wide range of scenarios by varying both SNP densities and the genetic relationships be

SUBMITTER: Palaiokostas C 

PROVIDER: S-EPMC6582704 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature