Acupuncture Regulating Gut Microbiota in Abdominal Obese Rats Induced by High-Fat Diet.

ABSTRACT:

Objective

To investigate the effects of acupuncture on metabolic health and gut microbiota dysbiosis in diet-induced abdominal obese model.

Materials and methods

Male Sprague-Dawley rats were randomly distributed into normal chow diet (NCD) group and high-fat diet (HFD) group. After 12 weeks of HFD feeding, an abdominal obese rat model was established. The abdominal obese rats were further assigned to acupuncture group (n=7) and nontreated HFD group (n=7). Acupuncture was applied to bilateral GB 26 of rats for 8 weeks. Subsequently, the body weight, waist circumference (WC), visceral fat mass, and liver weight were measured weekly in all rats. Metabolic parameters such as total cholesterol, triglyceride, alanine aminotransferase, aspartate transaminase, and blood glucose wer

SUBMITTER: Wang H 

PROVIDER: S-EPMC6582896 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature