Progression of anal intraepithelial neoplasia in HIV-positive individuals: predisposing factors.

ABSTRACT:

Background

The aim of the present study was to evaluate patient factors that affect the progression of anal dysplasia in human immunodeficiency virus (HIV)-positive individuals.

Methods

A retrospective cohort study of HIV-positive adults with human papilloma virus related anal lesions was performed from 2012 to 2017. All patients underwent surgical excision or biopsy and fulguration of lesions in the operating room without using high resolution anoscopy. Patients with initial presentation of squamous cell carcinoma were excluded. The study was designed to investigate progression between the first available histology and either the follow up histology or a negative examination. Patient files were reviewed and data was collected. A bivariate analysis of continuous and categori

SUBMITTER: McCutcheon T 

PROVIDER: S-EPMC6582960 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature