Air pollution and inflammation: Findings from concurrent repeated measures of systemic and reproductive tract cytokines during term pregnancy in Mexico City.

ABSTRACT:

Background

Environmental exposures are associated with a number of outcomes including adverse pregnancy outcomes. Although inflammation is hypothesized to play a role, the mechanistic pathways between environmental exposures and adverse health outcomes, including associations between exposures and longitudinal measures of systemic and reproductive tract inflammation, need elucidation.

Objectives

This study was conducted to evaluate whether exposure to air pollution is associated with immunologic responses in the systemic circulation and lower reproductive tract, and to evaluate whether systemic and reproductive tract immunologic responses are similar.

Methods

We quantified repeated measures of cytokines from cervico-vaginal exudates and serum obtained concurrently amo

SUBMITTER: Buxton MA 

PROVIDER: S-EPMC6582973 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature