The Latent Structure of Negative Symptoms in Schizophrenia.

ABSTRACT:

Importance

Negative symptoms are associated with a range of poor clinical outcomes, and currently available treatments generally do not produce a clinically meaningful response. Limited treatment progress may be owing in part to poor clarity regarding latent structure. Prior studies have inferred latent structure using exploratory factor analysis, which has led to the conclusion that there are 2 dimensions reflecting motivation and pleasure (MAP) and diminished expressivity (EXP) factors. However, whether these conclusions are statistically justified remains unclear because exploratory factor analysis does not test latent structure. Confirmatory factor analysis (CFA) is needed to test competing models regarding the latent structure of a construct.

Objective

To evaluate the f

SUBMITTER: Strauss GP 

PROVIDER: S-EPMC6583036 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature