A Long-term Benefit Approach vs Standard Risk-Based Approaches for Statin Eligibility in Primary Prevention.

ABSTRACT:

Importance

A 10-year benefit-based approach to statin therapy in primary prevention includes younger individuals with higher low-density lipoprotein cholesterol (LDL-C) and prevents more cardiovascular events than a risk-based approach. However, a 10-year treatment duration likely underestimates the expected benefits of statins.

Objective

To model the impact of a 30-year benefit approach to select individuals for statin therapy.

Design, setting, and participants

This cross-sectional analysis of the National Health and Nutrition Survey (NHANES) data set included samples of the US population from the 2009-2010, 2011-2012, and 2013-2014 data collection cycles. Individuals between 40 to 60 years old who did not have atherosclerotic cardiovascular disease, diabetes, or LDL

SUBMITTER: Thanassoulis G 

PROVIDER: S-EPMC6583050 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature