Use of Long-term Cumulative Blood Pressure in Cardiovascular Risk Prediction Models.

ABSTRACT:

Importance

Long-term cumulative systolic blood pressure (SBP) is significantly associated with increased rates of atherosclerotic cardiovascular disease (ASCVD) development independent of single SBP levels. However, published ASCVD risk prediction algorithms only include currently measured SBP.

Objective

To determine whether including long-term (5- and 10-year) cumulative SBP in risk equations improves the predictive ability compared with single SBP measurements.

Design, setting, and participants

Adults aged 45 to 65 years at the time of risk estimation with at least 20 years of follow-up (5 and 10 years prior to risk estimation and 10 years of event follow-up). The Lifetime Risk Pooling Project included data from the following cohorts: Coronary Artery Risk Developmen

SUBMITTER: Pool LR 

PROVIDER: S-EPMC6583053 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature