Accuracy of Complete Blood Cell Counts to Identify Febrile Infants 60 Days or Younger With Invasive Bacterial Infections.

ABSTRACT:

Importance

Clinicians often risk stratify young febrile infants for invasive bacterial infections (IBIs), defined as bacteremia and/or bacterial meningitis, using complete blood cell count parameters.

Objective

To estimate the accuracy of individual complete blood cell count parameters to identify febrile infants with IBIs.

Design, setting, and participants

Planned secondary analysis of a prospective observational cohort study comprising 26 emergency departments in the Pediatric Emergency Care Applied Research Network from 2008 to 2013. We included febrile (≥38°C), previously healthy, full-term infants younger than 60 days for whom blood cultures were obtained. All infants had either cerebrospinal fluid cultures or 7-day follow-up.

Main outcomes and measures

We

SUBMITTER: Cruz AT 

PROVIDER: S-EPMC6583058 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature