Effect of Dextroamphetamine on Poststroke Motor Recovery: A Randomized Clinical Trial.

ABSTRACT:

Importance

Data from animal models show that the administration of dextroamphetamine combined with task-relevant training facilitates recovery after focal brain injury. Results of clinical trials in patients with stroke have been inconsistent.

Objectives

To collect data important for future studies evaluating the effect of dextroamphetamine combined with physiotherapy for improving poststroke motor recovery and to test the efficacy of the approach.

Design, setting, participants

This pilot, double-blind, block-randomized clinical trial included patients with cortical or subcortical ischemic stroke and moderate or severe motor deficits from 5 rehabilitation hospitals or units. Participants were screened and enrolled from March 2001 through March 2003. The primary outcom

SUBMITTER: Goldstein LB 

PROVIDER: S-EPMC6583201 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature