Modeling Stroke Patient Transport for All Patients With Suspected Large-Vessel Occlusion.

ABSTRACT:

Importance

Ischemic stroke with large-vessel occlusion can be treated with alteplase and/or endovascular therapy; however, the administration of each treatment is time sensitive.

Objective

To identify the optimal triage and transport strategy: direct to the endovascular center (mothership) or immediate alteplase treatment followed by transfer to the endovascular center (drip and ship), for all patients with suspected large-vessel occlusion stroke.

Design setting, and participants

This was a theoretical, conditional probability modeling study. Existing data from clinical trials of stroke treatment were used for model generation. The study was conducted from February 1, 2017, to March 1, 2018.

Main outcomes and measures

The time-dependent efficacy of alteplase an

SUBMITTER: Holodinsky JK 

PROVIDER: S-EPMC6583214 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature