Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence.

ABSTRACT:

Importance

Individuals with adenomatous polyps are advised to undergo repeated colonoscopy surveillance to prevent subsequent colorectal cancer (CRC), but the relationship between adenomas at colonoscopy and long-term CRC incidence is unclear.

Objective

To compare long-term CRC incidence by colonoscopy adenoma findings.

Design, setting, and participants

Multicenter, prospective cohort study of participants in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer randomized clinical trial of flexible sigmoidoscopy (FSG) beginning in 1993 with follow-up for CRC incidence to 2013 across the United States. Participants included 154 900 men and women aged 55 to 74 years enrolled in PLCO of whom 15 935 underwent colonoscopy following their first positive FSG screening r

SUBMITTER: Click B 

PROVIDER: S-EPMC6583246 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature