Effect of an Intervention to Promote Breastfeeding on Asthma, Lung Function, and Atopic Eczema at Age 16 Years: Follow-up of the PROBIT Randomized Trial.

ABSTRACT:

Importance

Atopic diseases, including asthma and atopic eczema, are the most common chronic conditions of childhood.

Objective

To investigate whether an intervention to promote prolonged and exclusive breastfeeding protects against asthma, atopic eczema, and low lung function in adolescence.

Design, setting, and participants

Follow-up of the Promotion of Breastfeeding Intervention Trial (PROBIT), a cluster randomized trial in 30 Belarusian maternity hospitals and affiliated polyclinics; recruitment of 17 046 healthy term infants took place from June 15, 1996, to December 31, 1997. Data analysis was conducted from May 9, 2016, to April 21, 2017. The primary analytic approach was by modified intention-to-treat analysis.

Interventions

Randomization to receive a br

SUBMITTER: Flohr C 

PROVIDER: S-EPMC6583261 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature