Association of Chemerin Plasma Concentration With Risk of Colorectal Cancer.

ABSTRACT:

Importance

Inflammatory processes have been suggested to have an important role in colorectal cancer (CRC) etiology. Chemerin is a recently discovered inflammatory biomarker thought to exert chemotactic, adipogenic, and angiogenic functions. However, its potential link with CRC has not been sufficiently explored.

Objective

To evaluate the prospective association of circulating plasma chemerin concentrations with incident CRC.

Design, setting, and participants

Prospective case-cohort study based on 27 548 initially healthy participants from the European Prospective Investigation Into Cancer and Nutrition (EPIC)-Potsdam cohort who were followed for up to 16 years. Baseline study information and samples were collected between August 23, 1994, and September 25, 1998. Recr

SUBMITTER: Eichelmann F 

PROVIDER: S-EPMC6583278 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature