Assessment of Myocardial Function in Kenyan Children With Severe, Acute Malnutrition: The Cardiac Physiology in Malnutrition (CAPMAL) Study.

ABSTRACT:

Importance

Mortality among African children hospitalized with severe malnutrition remains high, with sudden, unexpected deaths leading to speculation about potential cardiac causes. Malnutrition is considered high risk for cardiac failure, but evidence is limited.

Objective

To investigate the role of cardiovascular dysfunction in African children with severe, acute malnutrition (SAM).

Design, setting, and participants

A prospective, matched case-control study, the Cardiac Physiology in Malnutrition (CAPMAL) study, of 88 children with SAM (exposed) vs 22 severity-matched patients without SAM (unexposed) was conducted between March 7, 2011, and February 20, 2012; data analysis was performed from October 1, 2012, to March 1, 2016.

Exposures

Echocardiographic and e

SUBMITTER: Brent B 

PROVIDER: S-EPMC6583281 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature