Association of Vasopressin Plus Catecholamine Vasopressors vs Catecholamines Alone With Atrial Fibrillation in Patients With Distributive Shock: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Vasopressin is an alternative to catecholamine vasopressors for patients with distributive shock-a condition due to excessive vasodilation, most frequently from severe infection. Blood pressure support with a noncatecholamine vasopressor may reduce stimulation of adrenergic receptors and decrease myocardial oxygen demand. Atrial fibrillation is common with catecholamines and is associated with adverse events, including mortality and increased length of stay (LOS).

Objectives

To determine whether treatment with vasopressin + catecholamine vasopressors compared with catecholamine vasopressors alone was associated with reductions in the risk of adverse events.

Data sources

MEDLINE, EMBASE, and CENTRAL were searched from inception to February 2018. Experts were

SUBMITTER: McIntyre WF 

PROVIDER: S-EPMC6583502 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature