Association Between Prenatal Alcohol Exposure and Craniofacial Shape of Children at 12 Months of Age.

ABSTRACT:

Importance

Children who receive a diagnosis of fetal alcohol spectrum disorder may have a characteristic facial appearance in addition to neurodevelopmental impairment. It is not well understood whether there is a gradient of facial characteristics of children who did not receive a diagnosis of fetal alcohol spectrum disorder but who were exposed to a range of common drinking patterns during pregnancy.

Objective

To examine the association between dose, frequency, and timing of prenatal alcohol exposure and craniofacial phenotype in 12-month-old children.

Design, setting, and participants

A prospective cohort study was performed from January 1, 2011, to December 30, 2014, among mothers recruited in the first trimester of pregnancy from low-risk, public maternity clinic

SUBMITTER: Muggli E 

PROVIDER: S-EPMC6583660 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature