Validity of a Novel Point-of-Care Troponin Assay for Single-Test Rule-Out of Acute Myocardial Infarction.

ABSTRACT:

Importance

Emergency department (ED) investigations of patients with suspected acute myocardial infarction (AMI) are time consuming, partly because of the turnaround time of laboratory tests. Current point-of-care troponin assays shorten test turnaround times but lack precision at lower concentrations. Development of point-of-care troponin assays with greater analytical precision could reduce the decision-making time in EDs for ruling out AMI.

Objective

To determine the clinical accuracy for AMI of a single troponin concentration measured on arrival to ED with a new-generation, higher precision point-of-care assay with a 15-minute turnaround time.

Design, setting, and participants

This observational study occurred at a single urban regional ED. Adults presenting acute

SUBMITTER: Pickering JW 

PROVIDER: S-EPMC6583693 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature