Effect of Platelet-Rich Plasma Injection for Rejuvenation of Photoaged Facial Skin: A Randomized Clinical Trial.

ABSTRACT:

Importance

There remains little experimental evidence and no randomized clinical trial to date to confirm the benefit of platelet-rich plasma (PRP) for facial rejuvenation.

Objective

To investigate whether PRP injection improves the visual appearance, including texture and color, of photodamaged facial skin.

Design, setting, and participants

In this randomized clinical trial, participants and raters were masked to groupings. The setting was an academic-based, urban outpatient dermatology practice in Chicago, Illinois. Participants were adults aged 18 to 70 years with bilateral cheek rhytids of Glogau class II or greater. The duration of the study was August 21, 2012, to February 16, 2016.

Interventions

Each participant received 3 mL intradermal injections of PR

SUBMITTER: Alam M 

PROVIDER: S-EPMC6583756 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature