Effect of Coaching to Increase Water Intake on Kidney Function Decline in Adults With Chronic Kidney Disease: The CKD WIT Randomized Clinical Trial.

ABSTRACT:

Importance

In observational studies, increased water intake is associated with better kidney function.

Objective

To determine the effect of coaching to increase water intake on kidney function in adults with chronic kidney disease.

Design, setting, and participants

The CKD WIT (Chronic Kidney Disease Water Intake Trial) randomized clinical trial was conducted in 9 centers in Ontario, Canada, from 2013 until 2017 (last day of follow-up, May 25, 2017). Patients had stage 3 chronic kidney disease (estimated glomerular filtration rate [eGFR] 30-60 mL/min/1.73 m2 and microalbuminuria or macroalbuminuria) and a 24-hour urine volume of less than 3.0 L.

Interventions

Patients in the hydration group (n = 316) were coached to drink more water, and those in the control gr

SUBMITTER: Clark WF 

PROVIDER: S-EPMC6583759 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature