Association of Human Papillomavirus Status at Head and Neck Carcinoma Subsites With Overall Survival.

ABSTRACT:

Importance

Data are limited on the prognostic value of human papillomavirus (HPV) status for head and neck carcinoma subsites.

Objective

To determine whether HPV positivity at each head and neck subsite is associated with improved overall survival.

Design, setting, and participants

This retrospective population-based cohort study used the National Cancer Database to identify patients diagnosed with head and neck squamous cell carcinomas from January 1, 2010, to December 31, 2014. Patients were classified according to the location of their primary malignancy into 1 of the 6 main subsites of the upper aerodigestive tract: oral cavity, oropharynx, nasopharynx, hypopharynx, larynx, and sinonasal tract. Patients were also classified by their HPV status. Data collection for

SUBMITTER: Li H 

PROVIDER: S-EPMC6583856 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature