Observational Outcomes of Initial Trabeculectomy With Mitomycin C in Patients of African Descent vs Patients of European Descent: Five-Year Results.

ABSTRACT:

Importance

There is evidence that patients of African descent (AD) experience higher surgical failure rate after trabeculectomy without antimetabolites.

Objective

To compare outcomes of initial trabeculectomy with mitomycin C in AD patients with those of patients of European descent (ED) and to identify prognostic factors for failure.

Design, setting, and participants

In this retrospective matched cohort study, 135 eyes of 105 AD patients were matched with 135 eyes of 117 ED patients by age (within 5 years), surgeon, lens status, and follow-up time (within 1 year) from a single tertiary academic center.

Interventions

Initial trabeculectomy with mitomycin C.

Main outcomes and measures

Criteria A, B, and C defined qualified success rates as final intraocul

SUBMITTER: Nguyen AH 

PROVIDER: S-EPMC6583864 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature