An automated and parallelised DIY-dosing unit for individual and complex feeding profiles: Construction, validation and applications.

ABSTRACT: Since biotechnological research becomes more and more important for industrial applications, there is an increasing need for scalable and controllable laboratory procedures. A widely used approach in biotechnological research to improve the performance of a process is to vary the growth rates in order to find the right balance between growth and the production. This can be achieved by the application of a suitable feeding strategy. During this initial bioprocess development, it is beneficial to have at hand cheap and easy setups that work in parallel (e.g. in shaking flasks). Unfortunately, there is a gap between these easy setups and defined and controllable processes, which are necessary for up-scaling to an industrial relevant volume. One prerequisite to test and evaluate different proc

SUBMITTER: Wagner SG 

PROVIDER: S-EPMC6583958 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature