Fretibacterium sp. human oral taxon 360 is a novel biomarker for periodontitis screening in the Japanese population.

ABSTRACT:

Background

Periodontitis is a common inflammatory disease, leading to bone destruction and tooth loss. Screening for periodontitis is important in preventing the progress of this disease. Various types of bacteria have been examined as potential screening targets, but only culturable pathogenic bacteria have been considered candidates. Recently, the various uncultivable bacteria have been identified in microbiome studies, but the value of these bacteria in periodontitis screening remains unknown.

Objectives

The aim of this study was to evaluate the diagnostic use of uncultivable bacteria Fretibacterium sp. HOT 360 and TM7 sp. HOT 356 for periodontitis screening in the Japanese population.

Material and methods

Stimulated saliva samples were collected from 217 participa

SUBMITTER: Khemwong T 

PROVIDER: S-EPMC6584019 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature